From the Cincinnati Enquirer
"Eastbound motorists on I-74 are being diverted to southbound Interstate 275 to Kilby Road, sheriff’s officials said. From there, motorists can get right back onto the ramp from Kilby Road to northbound I-275 to eastbound I-74.

While I-74 westbound remains open, motorists cannot use the ramp to I-275 south. They can take the Ohio 128 exit onto Ohio 128 and then take U.S. 50 to Kilby Road, which will return them to I-275."

Getting to Lawrenceburg from In. shouldn't be a problem. I can't tell if the exit from 275 north to 74 west is closed or not. If it is, getting back will mean a detour at 128. I'll drive by tomorrow and check this out before the 31st.
That second detour, for 275 south from west bound 74, is a long detour. I think I would go to the next exit on 74 for harrison and get back on east bound 74.