I ran a Bosch on alky with zero problems, had 6 years on it when I sold the car. Main thing is keeping the filters clean, both the injector filters and inline filter. I would recommend sending the injectors out to be professionally cleaned before the start of each season, not just squirting them with carb cleaner. Fuel pressure ?, depends on the injector size and what your doing for tuning, Power Commander? what type intake your running and so forth.